Varaico: Literature-Extracted Genetic Variants

PABPC4

71 papers

RefSeq Summary

Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encod...

Pfam Domains

RRM_1aa 13–83UCSCRNA recognition motif

RRM_1aa 101–168UCSCRNA recognition motif

RRM_1aa 193–261UCSCRNA recognition motif

RRM_1aa 296–364UCSCRNA recognition motif

MLLEaa 558–623UCSCMLLE domain

Gene Aliases

HGNC Name

poly(A) binding protein cytoplasmic 4

HGNC Alias Symbols

iPABP; APP-1

Papers

RefSeq ID

Protein change

DNA change

1–12 of 95 variants

2 papers

NM_001135653.2

p.L13insFs

c.37_38insA

2 papers

NM_001135653.2

p.V15V

c.45G>C

2 papers

NM_001135653.2

p.V37_L38insA

c.109_113ins3

2 papers

NM_001135653.2

p.T48P

c.142A>C

2 papers

NM_001135653.2

p.A65Splc

c.193+796C>G

2 papers

NM_001135653.2

p.R83H

c.248G>A

2 papers

NM_001135653.2

p.V168Splc

c.504-254C>A

2 papers

NM_001135653.2

p.T217I

c.650C>T

2 papers

NM_001135653.2

p.K246_A247Splc

c.738+85T>C

2 papers

NM_001135653.2

p.Q292_G293Splc

c.877-387C>T

2 papers

NM_001135653.2

p.I298L

c.892A>C

2 papers

NM_001135653.2

p.I320fs

c.958_959fs