Varaico: Literature-Extracted Genetic Variants

PABPC4

71 papers

RefSeq Summary

Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encod...

Pfam Domains

RRM_1aa 13–83UCSCRNA recognition motif

RRM_1aa 101–168UCSCRNA recognition motif

RRM_1aa 193–261UCSCRNA recognition motif

RRM_1aa 296–364UCSCRNA recognition motif

MLLEaa 558–623UCSCMLLE domain

Gene Aliases

HGNC Name

poly(A) binding protein cytoplasmic 4

HGNC Alias Symbols

iPABP; APP-1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001135653.2

p.S319insFs

c.956_957insA

Surrounding Variants

2 papers

NM_001135653.2

p.I320fs

c.958_959fs

1 paper

NM_001135653.2

p.D307Y

c.919G>T

2 papers

NM_001135653.2

p.I298L

c.892A>C

2 papers

NM_001135653.2

p.K324_V325Splc

c.972+53A>T

1 paper

NM_001135653.2

p.V294A

c.881T>C

2 papers

NM_001135653.2

p.Q292_G293Splc

c.877-387C>T

2 papers

NM_001135653.2

p.K324_V325Splc

c.972+704C>G

1 paper

NM_001135653.2

p.R290Q

c.869G>A

1 paper

NM_001135653.2

p.Q282*

c.844C>T

1 paper

NM_001135653.2

p.E281*

c.841G>T

1 paper

NM_001135653.2

p.E275Q

c.823G>C

1 paper

NM_001135653.2

p.R272Q

c.815G>A