Varaico: Literature-Extracted Genetic Variants

PABPC4

71 papers

RefSeq Summary

Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encod...

Pfam Domains

RRM_1aa 13–83UCSCRNA recognition motif

RRM_1aa 101–168UCSCRNA recognition motif

RRM_1aa 193–261UCSCRNA recognition motif

RRM_1aa 296–364UCSCRNA recognition motif

MLLEaa 558–623UCSCMLLE domain

Gene Aliases

HGNC Name

poly(A) binding protein cytoplasmic 4

HGNC Alias Symbols

iPABP; APP-1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001135653.2

p.D204G

c.611A>G

Surrounding Variants

1 paper

NM_001135653.2

p.E209Q

c.625G>C

1 paper

NM_001135653.2

p.G215C

c.643G>T

1 paper

NM_001135653.2

p.N192I

c.575A>T

1 paper

NM_001135653.2

p.K188R

c.563A>G

1 paper

NM_001135653.2

p.K188T

c.563A>C

1 paper

NM_001135653.2

p.G184R

c.550G>A

1 paper

NM_001135653.2

p.R179R

c.537G>A

1 paper

NM_001135653.2

p.R179Q

c.536G>A

1 paper

NM_001135653.2

p.R176C

c.526C>T

1 paper

NM_001135653.2

p.S175fs

c.523_524fs

1 paper

NM_001135653.2

p.S175F

c.524C>T

1 paper

NM_001135653.2

p.S175insFs

c.523dupT