Varaico: Literature-Extracted Genetic Variants

Gene:PAK2
Variant:p.P11P

PAK2

787 papers

RefSeq Summary

The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve ...

Pfam Domains

PBDaa 73–131UCSCP21-Rho-binding domain
Pkinaseaa 249–500UCSCProtein kinase domain

Gene Aliases

HGNC Name

p21 (RAC1) activated kinase 2

HGNC Alias Symbols

PAK65; PAKgamma

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002577.4
p.P11P
c.33T>A
Surrounding Variants
1 paper
NM_002577.4
p.P12A
c.34C>G
1 paper
NM_002577.4
p.P11T
c.31C>A
2 papers
NM_002577.4
p.P11S
c.31C>T
1 paper
NM_002577.4
p.P14S
c.40C>T
1 paper
NM_002577.4
p.D9Y
c.25G>T
1 paper
NM_002577.4
p.P14P
c.42T>A
1 paper
NM_002577.4
p.E8V
c.23A>T
1 paper
NM_002577.4
p.P15_V16insFs
c.45_46insT
1 paper
NM_002577.4
p.E8Q
c.22G>C
1 paper
NM_002577.4
p.V16V
c.48G>A
1 paper
NM_002577.4
p.G5A
c.14G>C
1 paper
NM_002577.4
p.S20_G26insFs
c.59_77dup19
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