Varaico: Literature-Extracted Genetic Variants

Gene:PAK2
Variant:p.P30fs

PAK2

787 papers

RefSeq Summary

The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve ...

Pfam Domains

PBDaa 73–131UCSCP21-Rho-binding domain
Pkinaseaa 249–500UCSCProtein kinase domain

Gene Aliases

HGNC Name

p21 (RAC1) activated kinase 2

HGNC Alias Symbols

PAK65; PAKgamma

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002577.4
p.P30fs
c.88_89fs
Surrounding Variants
1 paper
NM_002577.4
p.P30A
c.88C>G
1 paper
NM_002577.4
p.L31M
c.91T>A
1 paper
NM_002577.4
p.K28R
c.83A>G
1 paper
NM_002577.4
p.L31L
c.93G>A
1 paper
NM_002577.4
p.S32A
c.94T>G
1 paper
NM_002577.4
p.S32S
c.96A>G
2 papers
NM_002577.4
p.A33D
c.98C>A
1 paper
NM_002577.4
p.N34S
c.101A>G
1 paper
NM_002577.4
p.T25N
c.74C>A
1 paper
NM_002577.4
p.T25_G26delFs
c.75_76delTG
1 paper
NM_002577.4
p.H35L
c.104A>T
1 paper
NM_002577.4
p.S24R
c.72C>G
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