Varaico: Literature-Extracted Genetic Variants

Gene:PAK2
Variant:p.Q101H

PAK2

787 papers

RefSeq Summary

The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve ...

Pfam Domains

PBDaa 73–131UCSCP21-Rho-binding domain
Pkinaseaa 249–500UCSCProtein kinase domain

Gene Aliases

HGNC Name

p21 (RAC1) activated kinase 2

HGNC Alias Symbols

PAK65; PAKgamma

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
16 papers
NM_002577.4
p.Q101H
c.303G>T
Surrounding Variants
16 papers
NM_002577.4
p.Q101H
c.303G>C
1 paper
NM_002577.4
p.W102R
c.304T>A
1 paper
NM_002577.4
p.E100Q
c.298G>C
1 paper
NM_002577.4
p.P99insFs
c.295_296insG
1 paper
NM_002577.4
p.M98I
c.294G>A
1 paper
NM_002577.4
p.M98I
c.294G>C
1 paper
NM_002577.4
p.M98I
c.294G>T
1 paper
NM_002577.4
p.M98L
c.292A>C
1 paper
NM_002577.4
p.M98L
c.292A>T
1 paper
NM_002577.4
p.G97D
c.290G>A
5 papers
NM_002577.4
p.T96_G97Splc
c.289-1G>A
1 paper
NM_002577.4
p.T96_G97Splc
c.289-2A>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."