Varaico: Literature-Extracted Genetic Variants

Gene:PAK5
Variant:p.T538N

PAK5

200 papers

RefSeq Summary

The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulati...

Pfam Domains

PBDaa 10–67UCSCP21-Rho-binding domain
Pkinaseaa 449–700UCSCProtein kinase domain

Gene Aliases

HGNC Name

p21 (RAC1) activated kinase 5

HGNC Previous Symbol

PAK7

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
3 papers
NM_177990.4
p.T538N
c.1613C>A
Surrounding Variants
1 paper
NM_177990.4
p.T538S
c.1613C>G
1 paper
NM_177990.4
p.T538S
c.1612A>T
1 paper
NM_177990.4
p.H537_R539del0
c.1611_1616del6
1 paper
NM_177990.4
p.F525L
c.1575T>G
1 paper
NM_177990.4
p.F525L
c.1575T>A
1 paper
NM_177990.4
p.F525L
c.1573T>C
1 paper
NM_177990.4
p.V521L
c.1561G>T
1 paper
NM_177990.4
p.V521L
c.1561G>C
1 paper
NM_177990.4
p.E518K
c.1552G>A
1 paper
NM_177990.4
p.D517E
c.1551T>G
3 papers
NM_177990.4
p.D517N
c.1549G>A
1 paper
NM_177990.4
p.Y513H
c.1537T>C
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