Varaico: Literature-Extracted Genetic Variants

Gene:PAK5
Variant:p.D500N

PAK5

200 papers

RefSeq Summary

The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulati...

Pfam Domains

PBDaa 10–67UCSCP21-Rho-binding domain
Pkinaseaa 449–700UCSCProtein kinase domain

Gene Aliases

HGNC Name

p21 (RAC1) activated kinase 5

HGNC Previous Symbol

PAK7

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_177990.4
p.D500N
c.1498G>A
Surrounding Variants
1 paper
NM_177990.4
p.D500V
c.1499A>T
1 paper
NM_177990.4
p.D500E
c.1500T>G
1 paper
NM_177990.4
p.D500E
c.1500T>A
1 paper
NM_177990.4
p.V496_D500delFs
c.1488_1500del13
1 paper
NM_177990.4
p.Y501fs
c.1501_1502fs
1 paper
NM_177990.4
p.Y501_H502delFs
c.1502_1505del4
1 paper
NM_177990.4
p.I497fs
c.1489_1490fs
1 paper
NM_177990.4
p.V495V
c.1485C>T
1 paper
NM_177990.4
p.D504E
c.1512C>G
1 paper
NM_177990.4
p.D504E
c.1512C>A
1 paper
NM_177990.4
p.D508D
c.1524C>T
7 papers
NM_177990.4
p.S511N
c.1532G>A
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