Varaico: Literature-Extracted Genetic Variants

Gene:PAK5
Variant:p.K454T

PAK5

200 papers

RefSeq Summary

The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulati...

Pfam Domains

PBDaa 10–67UCSCP21-Rho-binding domain
Pkinaseaa 449–700UCSCProtein kinase domain

Gene Aliases

HGNC Name

p21 (RAC1) activated kinase 5

HGNC Previous Symbol

PAK7

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_177990.4
p.K454T
c.1361A>C
Surrounding Variants
1 paper
NM_177990.4
p.I455T
c.1364T>C
1 paper
NM_177990.4
p.A450V
c.1349C>T
1 paper
NM_177990.4
p.A450T
c.1348G>A
1 paper
NM_177990.4
p.S459T
c.1375T>A
1 paper
NM_177990.4
p.G461S
c.1381G>A
1 paper
NM_177990.4
p.E447D
c.1341A>T
1 paper
NM_177990.4
p.E447D
c.1341A>C
2 papers
NM_177990.4
p.E447K
c.1339G>A
2 papers
NM_177990.4
p.V463L
c.1387G>T
2 papers
NM_177990.4
p.V463L
c.1387G>C
1 paper
NM_177990.4
p.I465I
c.1395C>T
1 paper
NM_177990.4
p.A466T
c.1396G>A
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