Varaico: Literature-Extracted Genetic Variants

Gene:PAK5
Variant:p.T397M

PAK5

200 papers

RefSeq Summary

The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulati...

Pfam Domains

PBDaa 10–67UCSCP21-Rho-binding domain
Pkinaseaa 449–700UCSCProtein kinase domain

Gene Aliases

HGNC Name

p21 (RAC1) activated kinase 5

HGNC Previous Symbol

PAK7

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_177990.4
p.T397M
c.1190C>T
Surrounding Variants
1 paper
NM_177990.4
p.T397K
c.1190C>A
1 paper
NM_177990.4
p.A398T
c.1192G>A
1 paper
NM_177990.4
p.A398G
c.1193C>G
1 paper
NM_177990.4
p.I395L
c.1183A>C
1 paper
NM_177990.4
p.S392L
c.1175C>T
1 paper
NM_177990.4
p.S391G
c.1171A>G
1 paper
NM_177990.4
p.S409R
c.1225A>C
1 paper
NM_177990.4
p.S409R
c.1227C>G
1 paper
NM_177990.4
p.S409R
c.1227C>A
1 paper
NM_177990.4
p.P413P
c.1239G>A
1 paper
NM_177990.4
p.S375F
c.1124C>T
1 paper
NM_177990.4
p.S420P
c.1258T>C
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