Varaico: Literature-Extracted Genetic Variants

Gene:PAK5
Variant:p.R335P

PAK5

200 papers

RefSeq Summary

The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulati...

Pfam Domains

PBDaa 10–67UCSCP21-Rho-binding domain
Pkinaseaa 449–700UCSCProtein kinase domain

Gene Aliases

HGNC Name

p21 (RAC1) activated kinase 5

HGNC Previous Symbol

PAK7

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
10 papers
NM_177990.4
p.R335P
c.1004G>C
Surrounding Variants
1 paper
NM_177990.4
p.D334H
c.1000G>C
1 paper
NM_177990.4
p.Q337R
c.1010A>G
1 paper
NM_177990.4
p.D332E
c.996T>G
1 paper
NM_177990.4
p.D332E
c.996T>A
1 paper
NM_177990.4
p.L340I
c.1018C>A
1 paper
NM_177990.4
p.P342H
c.1025C>A
1 paper
NM_177990.4
p.G346R
c.1036G>C
1 paper
NM_177990.4
p.G346R
c.1036G>A
1 paper
NM_177990.4
p.G346G
c.1038G>T
1 paper
NM_177990.4
p.R352S
c.1056G>T
1 paper
NM_177990.4
p.R352S
c.1056G>C
1 paper
NM_177990.4
p.P354S
c.1060C>T
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