Varaico: Literature-Extracted Genetic Variants

Gene:PAK5
Variant:p.G258V

PAK5

200 papers

RefSeq Summary

The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulati...

Pfam Domains

PBDaa 10–67UCSCP21-Rho-binding domain
Pkinaseaa 449–700UCSCProtein kinase domain

Gene Aliases

HGNC Name

p21 (RAC1) activated kinase 5

HGNC Previous Symbol

PAK7

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_177990.4
p.G258V
c.773G>T
Surrounding Variants
1 paper
NM_177990.4
p.S253C
c.757A>T
1 paper
NM_177990.4
p.A251E
c.752C>A
1 paper
NM_177990.4
p.D265E
c.795C>G
1 paper
NM_177990.4
p.D265E
c.795C>A
1 paper
NM_177990.4
p.E248G
c.743A>G
1 paper
NM_177990.4
p.E248K
c.742G>A
1 paper
NM_177990.4
p.K247E
c.739A>G
1 paper
NM_177990.4
p.S243R
c.729C>G
1 paper
NM_177990.4
p.S243R
c.729C>A
1 paper
NM_177990.4
p.S243R
c.727A>C
2 papers
NM_177990.4
p.Q279K
c.835C>A
1 paper
NM_177990.4
p.S288A
c.862T>G
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