Varaico: Literature-Extracted Genetic Variants

Gene:PAK5
Variant:p.D204N

PAK5

200 papers

RefSeq Summary

The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulati...

Pfam Domains

PBDaa 10–67UCSCP21-Rho-binding domain
Pkinaseaa 449–700UCSCProtein kinase domain

Gene Aliases

HGNC Name

p21 (RAC1) activated kinase 5

HGNC Previous Symbol

PAK7

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_177990.4
p.D204N
c.610G>A
Surrounding Variants
1 paper
NM_177990.4
p.P209L
c.626C>T
2 papers
NM_177990.4
p.D198N
c.592G>A
1 paper
NM_177990.4
p.S210C
c.628A>T
3 papers
NM_177990.4
p.E211K
c.631G>A
1 paper
NM_177990.4
p.S190F
c.569C>T
1 paper
NM_177990.4
p.S223S
c.669G>A
1 paper
NM_177990.4
p.P227S
c.679C>T
1 paper
NM_177990.4
p.A180V
c.539C>T
1 paper
NM_177990.4
p.M175I
c.525G>T
1 paper
NM_177990.4
p.M175I
c.525G>C
1 paper
NM_177990.4
p.M175I
c.525G>A
5 papers
NM_177990.4
p.M173I
c.519G>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."