Varaico: Literature-Extracted Genetic Variants

Gene:PAK5
Variant:p.S99F

PAK5

200 papers

RefSeq Summary

The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulati...

Pfam Domains

PBDaa 10–67UCSCP21-Rho-binding domain
Pkinaseaa 449–700UCSCProtein kinase domain

Gene Aliases

HGNC Name

p21 (RAC1) activated kinase 5

HGNC Previous Symbol

PAK7

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_177990.4
p.S99F
c.296C>T
Surrounding Variants
1 paper
NM_177990.4
p.R96C
c.286C>T
1 paper
NM_177990.4
p.S104N
c.311G>A
1 paper
NM_177990.4
p.S93L
c.278C>T
1 paper
NM_177990.4
p.P106S
c.316C>T
1 paper
NM_177990.4
p.I92N
c.275T>A
1 paper
NM_177990.4
p.Q110R
c.329A>G
1 paper
NM_177990.4
p.D88A
c.263A>C
1 paper
NM_177990.4
p.H115Y
c.343C>T
1 paper
NM_177990.4
p.P117S
c.349C>T
1 paper
NM_177990.4
p.S81P
c.241T>C
2 papers
NM_177990.4
p.G118D
c.353G>A
1 paper
NM_177990.4
p.T80I
c.239C>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."