Varaico: Literature-Extracted Genetic Variants

Gene:PAK5
Variant:p.P27L

PAK5

200 papers

RefSeq Summary

The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulati...

Pfam Domains

PBDaa 10–67UCSCP21-Rho-binding domain
Pkinaseaa 449–700UCSCProtein kinase domain

Gene Aliases

HGNC Name

p21 (RAC1) activated kinase 5

HGNC Previous Symbol

PAK7

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_177990.4
p.P27L
c.80C>T
Surrounding Variants
1 paper
NM_177990.4
p.Q28L
c.83A>T
1 paper
NM_177990.4
p.F17C
c.50T>G
1 paper
NM_177990.4
p.S15F
c.44C>T
1 paper
NM_177990.4
p.W39C
c.117G>T
1 paper
NM_177990.4
p.W39C
c.117G>C
1 paper
NM_177990.4
p.P14S
c.40C>T
1 paper
NM_177990.4
p.G13R
c.37G>C
1 paper
NM_177990.4
p.D45N
c.133G>A
2 papers
NM_177990.4
p.K8N
c.24G>T
2 papers
NM_177990.4
p.K8N
c.24G>C
1 paper
NM_177990.4
p.N48S
c.143A>G
1 paper
NM_177990.4
p.K5I
c.14A>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."