Varaico: Literature-Extracted Genetic Variants

PALB2

2,283 papers

RefSeq Summary

This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the st...

Pfam Domains

PALB2_WD40aa 542–889UCSCPartner and localizer of BRCA2 WD40 domain

PALB2_WD40aa 1039–1105UCSCPartner and localizer of BRCA2 WD40 domain

Gene Aliases

HGNC Name

partner and localizer of BRCA2

HGNC Alias Symbols

FLJ21816; FANCN

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_024675.4

p.S955R

c.2863A>C

Surrounding Variants

1 paper

NM_024675.4

p.S955C

c.2863A>T

1 paper

NM_024675.4

p.S955G

c.2863A>G

1 paper

NM_024675.4

p.S955I

c.2864G>T

1 paper

NM_024675.4

p.S955T

c.2864G>C

1 paper

NM_024675.4

p.S955N

c.2864G>A

1 paper

NM_024675.4

p.S955delFs

c.2863delT

1 paper

NM_024675.4

p.E954D

c.2862A>T

1 paper

NM_024675.4

p.E954D

c.2862A>C

4 papers

NM_024675.4

p.S955R

c.2865T>G

4 papers

NM_024675.4

p.S955R

c.2865T>A

1 paper

NM_024675.4

p.R945_S955del0

c.2835_2864del30

1 paper

NM_024675.4

p.E954V

c.2861A>T