Varaico: Literature-Extracted Genetic Variants

PALB2

2,283 papers

RefSeq Summary

This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the st...

Pfam Domains

PALB2_WD40aa 542–889UCSCPartner and localizer of BRCA2 WD40 domain

PALB2_WD40aa 1039–1105UCSCPartner and localizer of BRCA2 WD40 domain

Gene Aliases

HGNC Name

partner and localizer of BRCA2

HGNC Alias Symbols

FLJ21816; FANCN

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024675.4

p.D953H

c.2857G>C

Surrounding Variants

1 paper

NM_024675.4

p.D953Y

c.2857G>T

1 paper

NM_024675.4

p.D953N

c.2857G>A

1 paper

NM_024675.4

p.D952E

c.2856T>G

1 paper

NM_024675.4

p.D952E

c.2856T>A

1 paper

NM_024675.4

p.D953V

c.2858A>T

1 paper

NM_024675.4

p.D953G

c.2858A>G

1 paper

NM_024675.4

p.D953A

c.2858A>C

2 papers

NM_024675.4

p.D953E

c.2859T>G

1 paper

NM_024675.4

p.D953D

c.2859T>C

2 papers

NM_024675.4

p.D953E

c.2859T>A

1 paper

NM_024675.4

p.D952V

c.2855A>T

1 paper

NM_024675.4

p.D952G

c.2855A>G