Varaico: Literature-Extracted Genetic Variants

PALB2

2,283 papers

RefSeq Summary

This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the st...

Pfam Domains

PALB2_WD40aa 542–889UCSCPartner and localizer of BRCA2 WD40 domain

PALB2_WD40aa 1039–1105UCSCPartner and localizer of BRCA2 WD40 domain

Gene Aliases

HGNC Name

partner and localizer of BRCA2

HGNC Alias Symbols

FLJ21816; FANCN

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024675.4

p.W904R

c.2710T>A

Surrounding Variants

1 paper

NM_024675.4

p.W904G

c.2710T>G

1 paper

NM_024675.4

p.W904R

c.2710T>C

1 paper

NM_024675.4

p.W904L

c.2711G>T

1 paper

NM_024675.4

p.W904S

c.2711G>C

10 papers

NM_024675.4

p.W904*

c.2711G>A

1 paper

NM_024675.4

p.A903_W904delFs

c.2709_2710delAA

1 paper

NM_024675.4

p.W904C

c.2712G>T

1 paper

NM_024675.4

p.W904C

c.2712G>C

10 papers

NM_024675.4

p.W904*

c.2712G>A

1 paper

NM_024675.4

p.A903V

c.2708C>T

1 paper

NM_024675.4

p.A903G

c.2708C>G

1 paper

NM_024675.4

p.D902_A903insFs

c.2704_2707dup4