Varaico: Literature-Extracted Genetic Variants

PALB2

2,283 papers

RefSeq Summary

This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the st...

Pfam Domains

PALB2_WD40aa 542–889UCSCPartner and localizer of BRCA2 WD40 domain

PALB2_WD40aa 1039–1105UCSCPartner and localizer of BRCA2 WD40 domain

Gene Aliases

HGNC Name

partner and localizer of BRCA2

HGNC Alias Symbols

FLJ21816; FANCN

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

10 papers

NM_024675.4

p.W898*

c.2694G>A

Surrounding Variants

1 paper

NM_024675.4

p.W898C

c.2694G>T

1 paper

NM_024675.4

p.W898C

c.2694G>C

1 paper

NM_024675.4

p.W898L

c.2693G>T

1 paper

NM_024675.4

p.W898S

c.2693G>C

10 papers

NM_024675.4

p.W898*

c.2693G>A

1 paper

NM_024675.4

p.K899E

c.2695A>G

1 paper

NM_024675.4

p.K899Q

c.2695A>C

1 paper

NM_024675.4

p.W898G

c.2692T>G

3 papers

NM_024675.4

p.W898R

c.2692T>C

3 papers

NM_024675.4

p.W898R

c.2692T>A

2 papers

NM_024675.4

p.K899I

c.2696A>T

1 paper

NM_024675.4

p.K899R

c.2696A>G