Varaico: Literature-Extracted Genetic Variants

PALB2

2,283 papers

RefSeq Summary

This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the st...

Pfam Domains

PALB2_WD40aa 542–889UCSCPartner and localizer of BRCA2 WD40 domain

PALB2_WD40aa 1039–1105UCSCPartner and localizer of BRCA2 WD40 domain

Gene Aliases

HGNC Name

partner and localizer of BRCA2

HGNC Alias Symbols

FLJ21816; FANCN

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_024675.4

p.G881D

c.2642G>A

Surrounding Variants

1 paper

NM_024675.4

p.G881V

c.2642G>T

1 paper

NM_024675.4

p.G881A

c.2642G>C

1 paper

NM_024675.4

p.G881delFs

c.2642delC

1 paper

NM_024675.4

p.G881fs

c.2641_2642fs

2 papers

NM_024675.4

p.G881C

c.2641G>T

1 paper

NM_024675.4

p.G881R

c.2641G>C

7 papers

NM_024675.4

p.G881S

c.2641G>A

1 paper

NM_024675.4

p.C882G

c.2644T>G

1 paper

NM_024675.4

p.C882R

c.2644T>C

1 paper

NM_024675.4

p.C882S

c.2644T>A

4 papers

NM_024675.4

p.C882fs

c.2644_2645fs

1 paper

NM_024675.4

p.A880A

c.2640C>T