Varaico: Literature-Extracted Genetic Variants

PALB2

2,283 papers

RefSeq Summary

This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the st...

Pfam Domains

PALB2_WD40aa 542–889UCSCPartner and localizer of BRCA2 WD40 domain

PALB2_WD40aa 1039–1105UCSCPartner and localizer of BRCA2 WD40 domain

Gene Aliases

HGNC Name

partner and localizer of BRCA2

HGNC Alias Symbols

FLJ21816; FANCN

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024675.4

p.F876C

c.2627T>G

Surrounding Variants

1 paper

NM_024675.4

p.F876S

c.2627T>C

1 paper

NM_024675.4

p.F876Y

c.2627T>A

1 paper

NM_024675.4

p.F876L

c.2628T>G

1 paper

NM_024675.4

p.F876V

c.2626T>G

1 paper

NM_024675.4

p.F876F

c.2628T>C

1 paper

NM_024675.4

p.F876L

c.2626T>C

2 papers

NM_024675.4

p.F876I

c.2626T>A

1 paper

NM_024675.4

p.F876L

c.2628T>A

1 paper

NM_024675.4

p.W877G

c.2629T>G

3 papers

NM_024675.4

p.W877R

c.2629T>C

2 papers

NM_024675.4

p.W877R

c.2629T>A

1 paper

NM_024675.4

p.M875I

c.2625G>T