Varaico: Literature-Extracted Genetic Variants

PALB2

2,283 papers

RefSeq Summary

This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the st...

Pfam Domains

PALB2_WD40aa 542–889UCSCPartner and localizer of BRCA2 WD40 domain

PALB2_WD40aa 1039–1105UCSCPartner and localizer of BRCA2 WD40 domain

Gene Aliases

HGNC Name

partner and localizer of BRCA2

HGNC Alias Symbols

FLJ21816; FANCN

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_024675.4

p.A874V

c.2621C>T

Surrounding Variants

1 paper

NM_024675.4

p.A874G

c.2621C>G

1 paper

NM_024675.4

p.A874D

c.2621C>A

1 paper

NM_024675.4

p.A874S

c.2620G>T

1 paper

NM_024675.4

p.A874P

c.2620G>C

2 papers

NM_024675.4

p.A874T

c.2620G>A

2 papers

NM_024675.4

p.S873delFs

c.2619delA

1 paper

NM_024675.4

p.A874fs

c.2620_2621fs

5 papers

NM_024675.4

p.S873R

c.2619T>G

5 papers

NM_024675.4

p.S873R

c.2619T>A

1 paper

NM_024675.4

p.M875L

c.2623A>T

1 paper

NM_024675.4

p.M875V

c.2623A>G

1 paper

NM_024675.4

p.M875L

c.2623A>C