Varaico: Literature-Extracted Genetic Variants

PALB2

2,283 papers

RefSeq Summary

This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the st...

Pfam Domains

PALB2_WD40aa 542–889UCSCPartner and localizer of BRCA2 WD40 domain

PALB2_WD40aa 1039–1105UCSCPartner and localizer of BRCA2 WD40 domain

Gene Aliases

HGNC Name

partner and localizer of BRCA2

HGNC Alias Symbols

FLJ21816; FANCN

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024675.4

p.S873G

c.2617A>G

Surrounding Variants

1 paper

NM_024675.4

p.S873C

c.2617A>T

5 papers

NM_024675.4

p.S873R

c.2617A>C

1 paper

NM_024675.4

p.S873I

c.2618G>T

1 paper

NM_024675.4

p.S873T

c.2618G>C

1 paper

NM_024675.4

p.S873N

c.2618G>A

5 papers

NM_024675.4

p.S873R

c.2619T>G

1 paper

NM_024675.4

p.V872G

c.2615T>G

2 papers

NM_024675.4

p.V872A

c.2615T>C

5 papers

NM_024675.4

p.S873R

c.2619T>A

1 paper

NM_024675.4

p.V872E

c.2615T>A

1 paper

NM_024675.4

p.A874S

c.2620G>T

1 paper

NM_024675.4

p.V872L

c.2614G>T