Varaico: Literature-Extracted Genetic Variants

PALB2

2,283 papers

RefSeq Summary

This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the st...

Pfam Domains

PALB2_WD40aa 542–889UCSCPartner and localizer of BRCA2 WD40 domain

PALB2_WD40aa 1039–1105UCSCPartner and localizer of BRCA2 WD40 domain

Gene Aliases

HGNC Name

partner and localizer of BRCA2

HGNC Alias Symbols

FLJ21816; FANCN

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_024675.4

p.G866delFs

c.2597delC

Surrounding Variants

1 paper

NM_024675.4

p.S867A

c.2599T>G

1 paper

NM_024675.4

p.S867P

c.2599T>C

1 paper

NM_024675.4

p.S867T

c.2599T>A

3 papers

NM_024675.4

p.G866V

c.2597G>T

1 paper

NM_024675.4

p.G866A

c.2597G>C

2 papers

NM_024675.4

p.G866D

c.2597G>A

2 papers

NM_024675.4

p.N863_G866delFs

c.2587_2596del10

3 papers

NM_024675.4

p.G866C

c.2596G>T

1 paper

NM_024675.4

p.G866R

c.2596G>C

4 papers

NM_024675.4

p.G866S

c.2596G>A

1 paper

NM_024675.4

p.S867F

c.2600C>T

1 paper

NM_024675.4

p.S867C

c.2600C>G