Varaico: Literature-Extracted Genetic Variants

PALB2

2,283 papers

RefSeq Summary

This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the st...

Pfam Domains

PALB2_WD40aa 542–889UCSCPartner and localizer of BRCA2 WD40 domain

PALB2_WD40aa 1039–1105UCSCPartner and localizer of BRCA2 WD40 domain

Gene Aliases

HGNC Name

partner and localizer of BRCA2

HGNC Alias Symbols

FLJ21816; FANCN

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024675.4

p.T458I

c.1373C>T

Surrounding Variants

1 paper

NM_024675.4

p.T458S

c.1373C>G

1 paper

NM_024675.4

p.T458T

c.1374T>C

1 paper

NM_024675.4

p.T458S

c.1372A>T

1 paper

NM_024675.4

p.T458A

c.1372A>G

1 paper

NM_024675.4

p.D459N

c.1375G>A

1 paper

NM_024675.4

p.E457D

c.1371A>T

1 paper

NM_024675.4

p.E457E

c.1371A>G

1 paper

NM_024675.4

p.E457D

c.1371A>C

1 paper

NM_024675.4

p.D459V

c.1376A>T

1 paper

NM_024675.4

p.E457V

c.1370A>T

2 papers

NM_024675.4

p.D459G

c.1376A>G

1 paper

NM_024675.4

p.E457G

c.1370A>G