Varaico: Literature-Extracted Genetic Variants

PALB2

2,283 papers

RefSeq Summary

This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the st...

Pfam Domains

PALB2_WD40aa 542–889UCSCPartner and localizer of BRCA2 WD40 domain

PALB2_WD40aa 1039–1105UCSCPartner and localizer of BRCA2 WD40 domain

Gene Aliases

HGNC Name

partner and localizer of BRCA2

HGNC Alias Symbols

FLJ21816; FANCN

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_024675.4

p.K152N

c.456G>T

Surrounding Variants

1 paper

NM_024675.4

p.K152insFs

c.455dupA

2 papers

NM_024675.4

p.K152N

c.456G>C

2 papers

NM_024675.4

p.K152K

c.456G>A

3 papers

NM_024675.4

p.R153W

c.457A>T

1 paper

NM_024675.4

p.K152M

c.455A>T

2 papers

NM_024675.4

p.R153G

c.457A>G

2 papers

NM_024675.4

p.K152R

c.455A>G

1 paper

NM_024675.4

p.K152T

c.455A>C

1 paper

NM_024675.4

p.R153M

c.458G>T

1 paper

NM_024675.4

p.R153T

c.458G>C

3 papers

NM_024675.4

p.R153K

c.458G>A

3 papers

NM_024675.4

p.K152*

c.454A>T