Varaico: Literature-Extracted Genetic Variants

PALB2

2,283 papers

RefSeq Summary

This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the st...

Pfam Domains

PALB2_WD40aa 542–889UCSCPartner and localizer of BRCA2 WD40 domain

PALB2_WD40aa 1039–1105UCSCPartner and localizer of BRCA2 WD40 domain

Gene Aliases

HGNC Name

partner and localizer of BRCA2

HGNC Alias Symbols

FLJ21816; FANCN

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024675.4

p.F107Y

c.320T>A

Surrounding Variants

1 paper

NM_024675.4

p.F107C

c.320T>G

2 papers

NM_024675.4

p.F107S

c.320T>C

2 papers

NM_024675.4

p.F107L

c.321T>G

1 paper

NM_024675.4

p.F107V

c.319T>G

3 papers

NM_024675.4

p.F107L

c.319T>C

1 paper

NM_024675.4

p.F107F

c.321T>C

3 papers

NM_024675.4

p.F107I

c.319T>A

2 papers

NM_024675.4

p.F107L

c.321T>A

1 paper

NM_024675.4

p.S106_F107delFs

c.317_320del4

1 paper

NM_024675.4

p.S106delFs

c.318delG

2 papers

NM_024675.4

p.S106S

c.318C>T

1 paper

NM_024675.4

p.N108Y

c.322A>T