Varaico: Literature-Extracted Genetic Variants

PALB2

2,283 papers

RefSeq Summary

This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the st...

Pfam Domains

PALB2_WD40aa 542–889UCSCPartner and localizer of BRCA2 WD40 domain

PALB2_WD40aa 1039–1105UCSCPartner and localizer of BRCA2 WD40 domain

Gene Aliases

HGNC Name

partner and localizer of BRCA2

HGNC Alias Symbols

FLJ21816; FANCN

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024675.4

p.K95insFs

c.284_285insG

Surrounding Variants

1 paper

NM_024675.4

p.K95M

c.284A>T

1 paper

NM_024675.4

p.K95R

c.284A>G

1 paper

NM_024675.4

p.K95T

c.284A>C

1 paper

NM_024675.4

p.T92_E94del3

c.274_281del9

1 paper

NM_024675.4

p.K95N

c.285G>T

1 paper

NM_024675.4

p.K95N

c.285G>C

2 papers

NM_024675.4

p.K95K

c.285G>A

2 papers

NM_024675.4

p.E94delFs

c.282delT

1 paper

NM_024675.4

p.E91_K95del0

c.273_284del12

1 paper

NM_024675.4

p.K95E

c.283A>G

1 paper

NM_024675.4

p.K95Q

c.283A>C

1 paper

NM_024675.4

p.K95_T96ins6

c.283_287ins18