Varaico: Literature-Extracted Genetic Variants

PALB2

2,283 papers

RefSeq Summary

This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the st...

Pfam Domains

PALB2_WD40aa 542–889UCSCPartner and localizer of BRCA2 WD40 domain

PALB2_WD40aa 1039–1105UCSCPartner and localizer of BRCA2 WD40 domain

Gene Aliases

HGNC Name

partner and localizer of BRCA2

HGNC Alias Symbols

FLJ21816; FANCN

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_024675.4

p.T92T

c.276T>A

Surrounding Variants

1 paper

NM_024675.4

p.T92T

c.276T>G

1 paper

NM_024675.4

p.T92T

c.276T>C

2 papers

NM_024675.4

p.G93R

c.277G>C

2 papers

NM_024675.4

p.G93R

c.277G>A

1 paper

NM_024675.4

p.T92I

c.275C>T

1 paper

NM_024675.4

p.T92S

c.275C>G

1 paper

NM_024675.4

p.T92N

c.275C>A

1 paper

NM_024675.4

p.G93fs

c.277_278fs

1 paper

NM_024675.4

p.G93V

c.278G>T

1 paper

NM_024675.4

p.G93A

c.278G>C

2 papers

NM_024675.4

p.G93E

c.278G>A

1 paper

NM_024675.4

p.T92S

c.274A>T