Varaico: Literature-Extracted Genetic Variants

PALB2

2,283 papers

RefSeq Summary

This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the st...

Pfam Domains

PALB2_WD40aa 542–889UCSCPartner and localizer of BRCA2 WD40 domain

PALB2_WD40aa 1039–1105UCSCPartner and localizer of BRCA2 WD40 domain

Gene Aliases

HGNC Name

partner and localizer of BRCA2

HGNC Alias Symbols

FLJ21816; FANCN

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_024675.4

p.P65S

c.193C>T

Surrounding Variants

1 paper

NM_024675.4

p.P65A

c.193C>G

1 paper

NM_024675.4

p.S64insFs

c.192dupA

1 paper

NM_024675.4

p.P65T

c.193C>A

1 paper

NM_024675.4

p.S64delFs

c.192delT

15 papers

NM_024675.4

p.P65L

c.194C>T

3 papers

NM_024675.4

p.P65R

c.194C>G

1 paper

NM_024675.4

p.P65insFs

c.194_195insA

2 papers

NM_024675.4

p.P65Q

c.194C>A

1 paper

NM_024675.4

p.S64S

c.192A>G

1 paper

NM_024675.4

p.P65P

c.195G>T

1 paper

NM_024675.4

p.P65_Q66insFs

c.195_196insA

2 papers

NM_024675.4

p.P65P

c.195G>A