Varaico: Literature-Extracted Genetic Variants

PAN2

69 papers

RefSeq Summary

This gene encodes a deadenylase that functions as the catalytic subunit of the polyadenylate binding protein dependent poly(A) nuclease complex. The encoded protein is a magnesium dependent 3' to 5' e...

Pfam Domains

PAN2_Naa 58–358UCSCPAN2 N-terminal

UCH_1aa 517–898UCSCUbiquitin carboxyl-terminal hydrolase

RNase_Taa 975–1147UCSCExonuclease

Gene Aliases

HGNC Name

poly(A) specific ribonuclease subunit PAN2

HGNC Previous Symbol

USP52

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014871.6

p.L1140F

c.3418C>T

Surrounding Variants

1 paper

NM_014871.6

p.Q1141*

c.3421C>T

1 paper

NM_001166279.3

p.E1137*

c.3409G>T

1 paper

NM_001166279.3

p.I1136insFs

c.3408dupT

2 papers

NM_001166279.3

p.S1054delFs

c.3162delG

NM_014871.6

p.S1051delFs

c.3153delG

2 papers

NM_001166279.3

p.S1055fs

c.3163_3164fs

NM_014871.6

p.S1052fs

c.3154_3155fs

1 paper

NM_014871.6

p.S1039L

c.3116C>T

1 paper

NM_014871.6

p.V1009D

c.3026T>A

1 paper

NM_014871.6

p.R1005S

c.3015G>T

1 paper

NM_014871.6

p.R1005S

c.3015G>C

1 paper

NM_014871.6

p.E986G

c.2957A>G

1 paper

NM_014871.6

p.V903insFs

c.2708dupT

1 paper

NM_014871.6

p.F889I

c.2665T>A