Varaico: Literature-Extracted Genetic Variants

PAN2

69 papers

RefSeq Summary

This gene encodes a deadenylase that functions as the catalytic subunit of the polyadenylate binding protein dependent poly(A) nuclease complex. The encoded protein is a magnesium dependent 3' to 5' e...

Pfam Domains

PAN2_Naa 58–358UCSCPAN2 N-terminal

UCH_1aa 517–898UCSCUbiquitin carboxyl-terminal hydrolase

RNase_Taa 975–1147UCSCExonuclease

Gene Aliases

HGNC Name

poly(A) specific ribonuclease subunit PAN2

HGNC Previous Symbol

USP52

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014871.6

p.K497E

c.1489A>G

Surrounding Variants

1 paper

NM_014871.6

p.K493_V494Splc

c.1480-17G>T

1 paper

NM_014871.6

p.P521H

c.1562C>A

1 paper

NM_014871.6

p.N525S

c.1574A>G

1 paper

NM_014871.6

p.R492C

c.1474C>T

2 papers

NM_014871.6

p.Y491Y

c.1473C>T

1 paper

NM_014871.6

p.S461*

c.1382C>G

1 paper

NM_014871.6

p.Q533_V534Splc

c.1600-3C>A

1 paper

NM_014871.6

p.A557A

c.1671A>G

1 paper

NM_014871.6

p.R571H

c.1712G>A

1 paper

NM_014871.6

p.E630G

c.1889A>G

1 paper

NM_014871.6

p.G654G

c.1962G>C

1 paper

NM_014871.6

p.R668H

c.2003G>A