Varaico: Literature-Extracted Genetic Variants

PAN2

69 papers

RefSeq Summary

This gene encodes a deadenylase that functions as the catalytic subunit of the polyadenylate binding protein dependent poly(A) nuclease complex. The encoded protein is a magnesium dependent 3' to 5' e...

Pfam Domains

PAN2_Naa 58–358UCSCPAN2 N-terminal

UCH_1aa 517–898UCSCUbiquitin carboxyl-terminal hydrolase

RNase_Taa 975–1147UCSCExonuclease

Gene Aliases

HGNC Name

poly(A) specific ribonuclease subunit PAN2

HGNC Previous Symbol

USP52

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014871.6

p.N327S

c.980A>G

Surrounding Variants

1 paper

NM_014871.6

p.N366N

c.1098C>T

1 paper

NM_014871.6

p.V380V

c.1140G>A

1 paper

NM_014871.6

p.P385S

c.1153C>T

1 paper

NM_014871.6

p.P385H

c.1154C>A

1 paper

NM_014871.6

p.D387G

c.1160A>G

1 paper

NM_014871.6

p.S389T

c.1166G>C

1 paper

NM_014871.6

p.D410H

c.1228G>C

1 paper

NM_014871.6

p.P418S

c.1252C>T

2 papers

NM_014871.6

p.R299C

c.895C>T

1 paper

NM_014871.6

p.P287S

c.859C>T

1 paper

NM_014871.6

p.T448A

c.1342A>G

1 paper

NM_014871.6

p.R451C

c.1351C>T