Varaico: Literature-Extracted Genetic Variants

PAN2

69 papers

RefSeq Summary

This gene encodes a deadenylase that functions as the catalytic subunit of the polyadenylate binding protein dependent poly(A) nuclease complex. The encoded protein is a magnesium dependent 3' to 5' e...

Pfam Domains

PAN2_Naa 58–358UCSCPAN2 N-terminal

UCH_1aa 517–898UCSCUbiquitin carboxyl-terminal hydrolase

RNase_Taa 975–1147UCSCExonuclease

Gene Aliases

HGNC Name

poly(A) specific ribonuclease subunit PAN2

HGNC Previous Symbol

USP52

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014871.6

p.R265H

c.794G>A

Surrounding Variants

1 paper

NM_014871.6

p.A251V

c.752C>T

1 paper

NM_014871.6

p.A250D

c.749C>A

1 paper

NM_014871.6

p.P287S

c.859C>T

2 papers

NM_014871.6

p.D241H

c.721G>C

2 papers

NM_014871.6

p.R299C

c.895C>T

1 paper

NM_014871.6

p.V218F

c.652G>T

1 paper

NM_014871.6

p.F208L

c.624C>G

1 paper

NM_014871.6

p.F208L

c.624C>A

1 paper

NM_014871.6

p.F208C

c.623T>G

1 paper

NM_014871.6

p.F208L

c.622T>C

1 paper

NM_014871.6

p.K191_Y192Splc

c.574-2A>G

1 paper

NM_014871.6

p.N327S

c.980A>G