Varaico: Literature-Extracted Genetic Variants

PARG

84 papers

RefSeq Summary

Poly(ADP-ribose) glycohydrolase (PARG) is the major enzyme responsible for the catabolism of poly(ADP-ribose), a reversible covalent-modifier of chromosomal proteins. The protein is found in many tiss...

Pfam Domains

PARG_cat_Naa 581–699UCSCPoly (ADP-ribose) glycohydrolase (PARG), helical domain

PARG_cat_Caa 705–909UCSCPoly (ADP-ribose) glycohydrolase (PARG), Macro domain fold

Gene Aliases

HGNC Name

poly(ADP-ribose) glycohydrolase

Papers

RefSeq ID

Protein change

DNA change

1–12 of 65 variants

3 papers

NM_003631.5

p.R485W

c.1453C>T

2 papers

NM_003631.5

p.E756A

c.2267A>C

2 papers

NM_003631.5

p.E756D

c.2268A>T

2 papers

NM_003631.5

p.E756D

c.2268A>C

1 paper

NM_003631.5

p.R13G

c.37C>G

1 paper

NM_003631.5

p.S26A

c.76T>G

1 paper

NM_003631.5

p.D27Y

c.79G>T

1 paper

NM_003631.5

p.R37G

c.109C>G

1 paper

NM_003631.5

p.D40A

c.119A>C

1 paper

NM_003631.5

p.G67V

c.200G>T

1 paper

NM_003631.5

p.Q76E

c.226C>G

1 paper

NM_003631.5

p.K75_Q76delFs

c.224_227del4