Varaico: Literature-Extracted Genetic Variants

PARG

84 papers

RefSeq Summary

Poly(ADP-ribose) glycohydrolase (PARG) is the major enzyme responsible for the catabolism of poly(ADP-ribose), a reversible covalent-modifier of chromosomal proteins. The protein is found in many tiss...

Pfam Domains

PARG_cat_Naa 581–699UCSCPoly (ADP-ribose) glycohydrolase (PARG), helical domain

PARG_cat_Caa 705–909UCSCPoly (ADP-ribose) glycohydrolase (PARG), Macro domain fold

Gene Aliases

HGNC Name

poly(ADP-ribose) glycohydrolase

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003631.5

p.Y682C

c.2045A>G

Surrounding Variants

1 paper

NM_003631.5

p.R685S

c.2055A>T

1 paper

NM_003631.5

p.R685S

c.2055A>C

1 paper

NM_003631.5

p.E688A

c.2063A>C

1 paper

NM_003631.5

p.L718V

c.2152T>G

1 paper

NM_003631.5

p.R663Splc

c.1988+913C>A