Varaico: Literature-Extracted Genetic Variants

PARG

84 papers

RefSeq Summary

Poly(ADP-ribose) glycohydrolase (PARG) is the major enzyme responsible for the catabolism of poly(ADP-ribose), a reversible covalent-modifier of chromosomal proteins. The protein is found in many tiss...

Pfam Domains

PARG_cat_Naa 581–699UCSCPoly (ADP-ribose) glycohydrolase (PARG), helical domain

PARG_cat_Caa 705–909UCSCPoly (ADP-ribose) glycohydrolase (PARG), Macro domain fold

Gene Aliases

HGNC Name

poly(ADP-ribose) glycohydrolase

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003631.5

p.H432R

c.1295A>G

Surrounding Variants

1 paper

NM_003631.5

p.P440S

c.1318C>T

1 paper

NM_003631.5

p.D450A

c.1349A>C

1 paper

NM_003631.5

p.R466Q

c.1397G>A

3 papers

NM_003631.5

p.R485W

c.1453C>T

1 paper

NM_003631.5

p.E421K

c.1261G>A

1 paper

NM_003631.5

p.D412A

c.1235A>C

1 paper

NM_003631.5

p.T411A

c.1231A>G

1 paper

NM_003631.5

p.K409R

c.1226A>G

1 paper

NM_003631.5

p.K409Q

c.1225A>C

1 paper

NM_003631.5

p.D407A

c.1220A>C

1 paper

NM_003631.5

p.H403Y

c.1207C>T

1 paper

NM_003631.5

p.T359I

c.1076C>T