Varaico: Literature-Extracted Genetic Variants

PARG

84 papers

RefSeq Summary

Poly(ADP-ribose) glycohydrolase (PARG) is the major enzyme responsible for the catabolism of poly(ADP-ribose), a reversible covalent-modifier of chromosomal proteins. The protein is found in many tiss...

Pfam Domains

PARG_cat_Naa 581–699UCSCPoly (ADP-ribose) glycohydrolase (PARG), helical domain

PARG_cat_Caa 705–909UCSCPoly (ADP-ribose) glycohydrolase (PARG), Macro domain fold

Gene Aliases

HGNC Name

poly(ADP-ribose) glycohydrolase

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003631.5

p.T174T

c.522A>G

Surrounding Variants

1 paper

NM_003631.5

p.E165A

c.494A>C

1 paper

NM_003631.5

p.N159I

c.476A>T

1 paper

NM_003631.5

p.D195V

c.584A>T

1 paper

NM_003631.5

p.Y145*

c.435T>G

1 paper

NM_003631.5

p.P138L

c.413C>T

1 paper

NM_003631.5

p.L211P

c.632T>C

1 paper

NM_003631.5

p.E224_Q227del4

c.670_680del12

1 paper

NM_003631.5

p.S238G

c.712A>G

1 paper

NM_003631.5

p.R105S

c.315A>T

1 paper

NM_003631.5

p.D253E

c.759T>G

1 paper

NM_003631.5

p.D253E

c.759T>A

1 paper

NM_003631.5

p.G289E

c.866G>A