Varaico: Literature-Extracted Genetic Variants

Gene:PARN
Variant:p.A394T

PARN

231 papers

RefSeq Summary

The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mR...

Pfam Domains

CAF1aa 3–390UCSCCAF1 family ribonuclease
RNA_bindaa 437–515UCSCRNA binding domain

Gene Aliases

HGNC Name

poly(A)-specific ribonuclease

HGNC Alias Symbol

DAN

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002582.4
p.A394T
c.1180G>A
Surrounding Variants
1 paper
NM_002582.4
p.M393T
c.1178T>C
1 paper
NM_002582.4
p.M393V
c.1177A>G
1 paper
NM_002582.4
p.N395S
c.1184A>G
1 paper
NM_002582.4
p.Y396D
c.1186T>G
1 paper
NM_002582.4
p.S392T
c.1174T>A
2 papers
NM_002582.4
p.I391T
c.1172T>C
1 paper
NM_002582.4
p.L397L
c.1189C>T
1 paper
NM_002582.4
p.L397V
c.1189C>G
1 paper
NM_002582.4
p.I391F
c.1171A>T
1 paper
NM_002582.4
p.I391V
c.1171A>G
1 paper
NM_002582.4
p.L397P
c.1190T>C
1 paper
NM_002582.4
p.F390L
c.1170C>G
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."