Varaico: Literature-Extracted Genetic Variants

Gene:PARN
Variant:p.T386K

PARN

231 papers

RefSeq Summary

The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mR...

Pfam Domains

CAF1aa 3–390UCSCCAF1 family ribonuclease
RNA_bindaa 437–515UCSCRNA binding domain

Gene Aliases

HGNC Name

poly(A)-specific ribonuclease

HGNC Alias Symbol

DAN

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002582.4
p.T386K
c.1157C>A
Surrounding Variants
1 paper
NM_002582.4
p.T386R
c.1157C>G
1 paper
NM_002582.4
p.T386A
c.1156A>G
2 papers
NM_002582.4
p.G387R
c.1159G>C
2 papers
NM_002582.4
p.G387R
c.1159G>A
1 paper
NM_002582.4
p.G387fs
c.1159_1160fs
1 paper
NM_002582.4
p.G387E
c.1160G>A
1 paper
NM_002582.4
p.T386_G387delFs
c.1158_1159delCT
1 paper
NM_002582.4
p.I385V
c.1153A>G
1 paper
NM_002582.4
p.L388M
c.1162C>A
3 papers
NM_002582.4
p.Y384C
c.1151A>G
8 papers
NM_002582.4
p.A383V
c.1148C>T
1 paper
NM_002582.4
p.A383G
c.1148C>G
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