Varaico: Literature-Extracted Genetic Variants

Gene:PARN
Variant:p.D370G

PARN

231 papers

RefSeq Summary

The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mR...

Pfam Domains

CAF1aa 3–390UCSCCAF1 family ribonuclease
RNA_bindaa 437–515UCSCRNA binding domain

Gene Aliases

HGNC Name

poly(A)-specific ribonuclease

HGNC Alias Symbol

DAN

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002582.4
p.D370G
c.1109A>G
Surrounding Variants
1 paper
NM_002582.4
p.Y369*
c.1107T>G
1 paper
NM_002582.4
p.Y369*
c.1107T>A
1 paper
NM_002582.4
p.Y369delFs
c.1105delA
1 paper
NM_002582.4
p.Y369fs
c.1105_1106fs
1 paper
NM_002582.4
p.A372T
c.1114G>A
2 papers
NM_002582.4
p.S368C
c.1102A>T
1 paper
NM_002582.4
p.S368G
c.1102A>G
1 paper
NM_002582.4
p.P367P
c.1101A>G
1 paper
NM_002582.4
p.P367delFs
c.1100delG
1 paper
NM_002582.4
p.S373C
c.1118C>G
1 paper
NM_002582.4
p.P367Q
c.1100C>A
1 paper
NM_002582.4
p.P367S
c.1099C>T
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."