Varaico: Literature-Extracted Genetic Variants

Gene:PARN
Variant:p.G365A

PARN

231 papers

RefSeq Summary

The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mR...

Pfam Domains

CAF1aa 3–390UCSCCAF1 family ribonuclease
RNA_bindaa 437–515UCSCRNA binding domain

Gene Aliases

HGNC Name

poly(A)-specific ribonuclease

HGNC Alias Symbol

DAN

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002582.4
p.G365A
c.1094G>C
Surrounding Variants
1 paper
NM_002582.4
p.G365R
c.1093G>C
1 paper
NM_002582.4
p.G365S
c.1093G>A
1 paper
NM_002582.4
p.E364G
c.1091A>G
1 paper
NM_002582.4
p.E364K
c.1090G>A
1 paper
NM_002582.4
p.P367S
c.1099C>T
2 papers
NM_002582.4
p.F366insFs
c.1098dupT
2 papers
NM_002582.4
p.P367fs
c.1099_1100fs
1 paper
NM_002582.4
p.P367Q
c.1100C>A
1 paper
NM_002582.4
p.A363T
c.1087G>A
1 paper
NM_002582.4
p.P367P
c.1101A>G
1 paper
NM_002582.4
p.P367delFs
c.1100delG
2 papers
NM_002582.4
p.S368C
c.1102A>T
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