Varaico: Literature-Extracted Genetic Variants

Gene:PARN
Variant:p.P357insFs

PARN

231 papers

RefSeq Summary

The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mR...

Pfam Domains

CAF1aa 3–390UCSCCAF1 family ribonuclease
RNA_bindaa 437–515UCSCRNA binding domain

Gene Aliases

HGNC Name

poly(A)-specific ribonuclease

HGNC Alias Symbol

DAN

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002582.4
p.P357insFs
c.1069_1070insAC
Surrounding Variants
1 paper
NM_002582.4
p.P357S
c.1069C>T
1 paper
NM_002582.4
p.P357A
c.1069C>G
1 paper
NM_002582.4
p.P357T
c.1069C>A
2 papers
NM_002582.4
p.P357L
c.1070C>T
1 paper
NM_002582.4
p.N356S
c.1067A>G
1 paper
NM_002582.4
p.N356T
c.1067A>C
1 paper
NM_002582.4
p.N356D
c.1066A>G
1 paper
NM_002582.4
p.N356H
c.1066A>C
1 paper
NM_002582.4
p.P358R
c.1073C>G
1 paper
NM_002582.4
p.K359E
c.1075A>G
2 papers
NM_002582.4
p.P354L
c.1061C>T
1 paper
NM_002582.4
p.P354H
c.1061C>A
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