Varaico: Literature-Extracted Genetic Variants

Gene:PARN
Variant:p.D336A

PARN

231 papers

RefSeq Summary

The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mR...

Pfam Domains

CAF1aa 3–390UCSCCAF1 family ribonuclease
RNA_bindaa 437–515UCSCRNA binding domain

Gene Aliases

HGNC Name

poly(A)-specific ribonuclease

HGNC Alias Symbol

DAN

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002582.4
p.D336A
c.1007A>C
Surrounding Variants
1 paper
NM_002582.4
p.D336V
c.1007A>T
1 paper
NM_002582.4
p.D336G
c.1007A>G
1 paper
NM_002582.4
p.D336Y
c.1006G>T
1 paper
NM_002582.4
p.D336N
c.1006G>A
1 paper
NM_002582.4
p.I337V
c.1009A>G
2 papers
NM_002582.4
p.K335_D336Splc
c.1006-2A>G
1 paper
NM_002582.4
p.I338T
c.1013T>C
2 papers
NM_002582.4
p.K335_D336Splc
c.1006-11G>A
1 paper
NM_002582.4
p.N340S
c.1019A>G
1 paper
NM_002582.4
p.S342A
c.1024T>G
1 paper
NM_002582.4
p.S342F
c.1025C>T
1 paper
NM_002582.4
p.S342C
c.1025C>G
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