Varaico: Literature-Extracted Genetic Variants

Gene:PARN
Variant:p.I241S

PARN

231 papers

RefSeq Summary

The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mR...

Pfam Domains

CAF1aa 3–390UCSCCAF1 family ribonuclease
RNA_bindaa 437–515UCSCRNA binding domain

Gene Aliases

HGNC Name

poly(A)-specific ribonuclease

HGNC Alias Symbol

DAN

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002582.4
p.I241S
c.722T>G
Surrounding Variants
1 paper
NM_002582.4
p.I241M
c.723C>G
1 paper
NM_002582.4
p.K235_I241delFs
c.704_722del19
1 paper
NM_002582.4
p.I241F
c.721A>T
1 paper
NM_002582.4
p.I241V
c.721A>G
1 paper
NM_002582.4
p.S242G
c.724A>G
1 paper
NM_002582.4
p.S242R
c.724A>C
1 paper
NM_002582.4
p.S242I
c.725G>T
1 paper
NM_002582.4
p.V240I
c.718G>A
1 paper
NM_002582.4
p.S242R
c.726C>G
1 paper
NM_002582.4
p.S242R
c.726C>A
1 paper
NM_002582.4
p.I239M
c.717A>G
1 paper
NM_002582.4
p.I239insFs
c.715dupA
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