Varaico: Literature-Extracted Genetic Variants

Gene:PARN
Variant:p.K179del1

PARN

231 papers

RefSeq Summary

The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mR...

Pfam Domains

CAF1aa 3–390UCSCCAF1 family ribonuclease
RNA_bindaa 437–515UCSCRNA binding domain

Gene Aliases

HGNC Name

poly(A)-specific ribonuclease

HGNC Alias Symbol

DAN

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002582.4
p.K179del1
c.535_536delCTT
Surrounding Variants
1 paper
NM_002582.4
p.K178_K179delFs
c.532_536del5
1 paper
NM_002582.4
p.K179M
c.536A>T
1 paper
NM_002582.4
p.K179R
c.536A>G
1 paper
NM_002582.4
p.K179T
c.536A>C
1 paper
NM_002582.4
p.K178_K179delFs
c.534_535delTC
1 paper
NM_002582.4
p.K179fs
c.535_536fs
1 paper
NM_002582.4
p.K179*
c.535A>T
1 paper
NM_002582.4
p.F180insFs
c.540dupT
1 paper
NM_002582.4
p.I181T
c.542T>C
1 paper
NM_002582.4
p.K178N
c.534G>T
1 paper
NM_002582.4
p.K178N
c.534G>C
1 paper
NM_002582.4
p.K178fs
c.532_533fs
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