Varaico: Literature-Extracted Genetic Variants

Gene:PARN
Variant:p.Q177R

PARN

231 papers

RefSeq Summary

The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mR...

Pfam Domains

CAF1aa 3–390UCSCCAF1 family ribonuclease
RNA_bindaa 437–515UCSCRNA binding domain

Gene Aliases

HGNC Name

poly(A)-specific ribonuclease

HGNC Alias Symbol

DAN

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002582.4
p.Q177R
c.530A>G
Surrounding Variants
7 papers
NM_002582.4
p.Q177*
c.529C>T
1 paper
NM_002582.4
p.Q177E
c.529C>G
1 paper
NM_002582.4
p.Q177H
c.531A>T
1 paper
NM_002582.4
p.Q177H
c.531A>C
1 paper
NM_002582.4
p.K178fs
c.532_533fs
1 paper
NM_002582.4
p.K178N
c.534G>T
1 paper
NM_002582.4
p.K178N
c.534G>C
1 paper
NM_002582.4
p.K179fs
c.535_536fs
1 paper
NM_002582.4
p.K179*
c.535A>T
1 paper
NM_002582.4
p.K179M
c.536A>T
1 paper
NM_002582.4
p.K179R
c.536A>G
1 paper
NM_002582.4
p.K179T
c.536A>C
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