Varaico: Literature-Extracted Genetic Variants

Gene:PARN
Variant:p.T172P

PARN

231 papers

RefSeq Summary

The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mR...

Pfam Domains

CAF1aa 3–390UCSCCAF1 family ribonuclease
RNA_bindaa 437–515UCSCRNA binding domain

Gene Aliases

HGNC Name

poly(A)-specific ribonuclease

HGNC Alias Symbol

DAN

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002582.4
p.T172P
c.514A>C
Surrounding Variants
1 paper
NM_002582.4
p.T172fs
c.514_515fs
1 paper
NM_002582.4
p.T172M
c.515C>T
2 papers
NM_002582.4
p.T172insFs
c.514dupA
1 paper
NM_002582.4
p.V171A
c.512T>C
1 paper
NM_002582.4
p.V171L
c.511G>C
1 paper
NM_002582.4
p.I173V
c.517A>G
1 paper
NM_002582.4
p.P170L
c.509C>T
1 paper
NM_002582.4
p.P170R
c.509C>G
1 paper
NM_002582.4
p.P170S
c.508C>T
1 paper
NM_002582.4
p.P174L
c.521C>T
1 paper
NM_002582.4
p.C169S
c.506G>C
1 paper
NM_002582.4
p.C169Y
c.506G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."