Varaico: Literature-Extracted Genetic Variants

Gene:PARN
Variant:p.S160P

PARN

231 papers

RefSeq Summary

The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mR...

Pfam Domains

CAF1aa 3–390UCSCCAF1 family ribonuclease
RNA_bindaa 437–515UCSCRNA binding domain

Gene Aliases

HGNC Name

poly(A)-specific ribonuclease

HGNC Alias Symbol

DAN

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002582.4
p.S160P
c.478T>C
Surrounding Variants
1 paper
NM_002582.4
p.S160F
c.479C>T
1 paper
NM_002582.4
p.S160C
c.479C>G
1 paper
NM_002582.4
p.L159R
c.476T>G
1 paper
NM_002582.4
p.Y161D
c.481T>G
1 paper
NM_002582.4
p.Y161H
c.481T>C
4 papers
NM_002582.4
p.Y161C
c.482A>G
1 paper
NM_002582.4
p.Y161*
c.483T>G
1 paper
NM_002582.4
p.Y161*
c.483T>A
1 paper
NM_002582.4
p.A158V
c.473C>T
1 paper
NM_002582.4
p.V162L
c.484G>T
1 paper
NM_002582.4
p.V162L
c.484G>C
1 paper
NM_002582.4
p.A158P
c.472G>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."