Varaico: Literature-Extracted Genetic Variants

Gene:PARN
Variant:p.Q109*

PARN

231 papers

RefSeq Summary

The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mR...

Pfam Domains

CAF1aa 3–390UCSCCAF1 family ribonuclease
RNA_bindaa 437–515UCSCRNA binding domain

Gene Aliases

HGNC Name

poly(A)-specific ribonuclease

HGNC Alias Symbol

DAN

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_002582.4
p.Q109*
c.325C>T
Surrounding Variants
1 paper
NM_002582.4
p.V107_C108delFs
c.321_324del4
1 paper
NM_002582.4
p.Q109P
c.326A>C
1 paper
NM_002582.4
p.C108delFs
c.322delA
1 paper
NM_002582.4
p.C108fs
c.322_323fs
1 paper
NM_002582.4
p.Q109_S110Splc
c.327+2T>C
1 paper
NM_002582.4
p.V107A
c.320T>C
2 papers
NM_002582.4
p.V107I
c.319G>A
1 paper
NM_002582.4
p.F106delFs
c.318delA
1 paper
NM_002582.4
p.F106S
c.317T>C
1 paper
NM_002582.4
p.F106fs
c.316_317fs
1 paper
NM_002582.4
p.K105R
c.314A>G
1 paper
NM_002582.4
p.V104G
c.311T>G
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